megatomi.com for Dummies
megatomi.com for Dummies
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Our new Obvious+ tissue clearing approach is the sole method that delipidates samples with no improve in morphology and with minimal influence on structural integrity.
Megatome is usually a vibrating microtome built to area a wide variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome enables significant-throughput tissue sectioning with uniform floor profile, along with minimum tissue damage and knowledge reduction.
Ask for a quote or demo Uniformly portion substantial tissues & sample arrays Megatome is the one microtome that could segment samples as large as intact nonhuman primate and human organs, rendering it priceless for fields such as neuropathology.
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SE makes use of a rotational electric powered discipline to disperse highly electromobile molecules (including antibodies or surfactant micelles) all over a porous sample without having harming electrically charged buildings inside the tissue. This allows 2-four working day clearing of intact organs,
Our preformulated EasyIndex Alternative raises and homogenize the refractive index of delipidated tissue samples, rendering them completely clear. This enables light-weight penetration into the sample and makes certain the acquisition of high-resolution, in-emphasis graphic info.
Megatome is really a novel microtome that permits for prime-precision sectioning of a wide array of tissue samples – from megatomi.com organoids, to arrays of animal organs, to intact human Mind hemispheres – with negligible tissue damage and data reduction.
eFLASH is often a immediate tissue labeling technique that allows for uniform entire-organ staining in 20 rounds of labeling.
Entirely delipidate complete mouse brains or comparably sized samples in just one day with SmartBatch+, or in one week with our passive clearing package.
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SHIELD avoids the variability of hydrogel embedding and the data reduction from PFA preservation, guarding specimens for various rounds of processing.
Leverage the Distinct+ tissue clearing system, in addition to eFLASH and patented stochastic electrotransport technologies, to promptly distinct and label full organs. Essential highlights and attributes include things like:
Our novel Defend tissue preservation system kinds intramolecular bonds making use of polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.